Methylation Test

Uncover Genetic Predispositions and Needs for Nutritional Support to Help Focus Supplementation


The Methylation Panel is an innovative test designed to offer insight into the critical biochemical methylation pathway.The results are synthesized on a front-page Interpretation-at-a-Glance (IAAG) graphic for quick methylation status assessment. Within the report, results are shown in a methylation pathway graphic to provide a clear understanding of the biochemistry involved.


Methylation is a chemical process that happens billions of times per second in every cell of the body. Methyl groups are transferred and donated between many different molecules which change their structure and function. Methyl groups act like billions of switches which turn genes on or off, help regulate mood, detoxify hormones, produce energy, and promote healthy aging.


Vitamins, minerals, and amino acids from the diet are needed to keep this process running smoothly. There are also genetic factors and oxidative stressors which can affect how well this pathway works.


Methylation is needed to create DNA and RNA and regulate gene expression. It helps make creatine, which is needed for skeletal muscle contraction. Methylation is involved in basic energy production, fat metabolism, immune responses, vascular health, and cell membrane repair. It produces and metabolizes neurotransmitters to regulate mood. Methylation also works to neutralize toxins and hormones.


When the methylation cycle is turned “off” due to lack of proper nutrients or genetic variants, a number of important molecules cannot be produced, including glutathione, CoQ10, epinephrine, melatonin, and serotonin – important hormones and antioxidants.


Methylation defects have been associated with many clinical conditions including, but not limited to cancer, autism, ADHD, congenital and neural tube defects, cognitive decline, depression, cardiovascular disease, and schizophrenia.


Genova’s Methylation Panel combines biomarkers with genetic information in one profile. Some genetic predispositions are not always expressed, therefore seeing combined results offers greater insight.


Not only does the Methylation Panel assess the methylation cycle, but it also incorporates the folate cycle and transsulfuration. Because these three processes are interconnected, the Methylation Panel is able to provide a complete picture regarding methylation status.


With these results, Vitalife can help tailor a personalized program to help target nutrient deficiencies. We source pre-methylated nutrients like Methylcobalamin (Vitamin B12) and Folate (Folic Acid) to help take out the guesswork and give your body proper nutrients that it can absorb and use. We can also support low levels of glutathione, CoQ10, carnitine, taurine, and other vital molecules produced by the methylation cycle to help target deficiencies and relieve symptoms.

Methylation Pathways
methylation pathways
main nutrients used in methyl cycle
Molecules produced by methyl cycle

a Draw

Get started by scheduling a lab draw online or over the phone. Draws are done Monday thru Friday prior to 5:30 for overnight delivery to our lab partners.

Wait on

Results may take up to two weeks for Methylation panels. A member of our staff will schedule your follow up consult at your draw and results will be uploaded to your client profile.

Start a

After the results are ready, our medical staff will develop a personalized program based on your results and will recommend treatment options in your follow-up consult.

How to Get Started


Our Lab Tests

Comprehensive nutrition test for nutrient deficiencies, amino acid levels, essential and metabolic fatty acids, organic acids, and overall oxidative stress.

Tests your body’s inflammatory response to 170 foods, additives, and food-chemicals and includes a complete diet program to help combat inflammation.

Advanced heart health assessment of lipids and cardiometabolic analytes to take a broader look at your cardiac health to develop targeted nutritional therapies.

Test for imbalances in the essential sex hormones: progesterone, estrogen, and testosterone, as well as other vital hormones controlling optimal health.

Test of your G6PD levels, a natural enzyme that protects your red blood cells from oxidative stress. Required for Ozone and Vitamin C drips over 25 grams.

Test for genetic predispositions that can affect vitamin and amino acid uptake, helping focus supplementation to override potential methylation defects.

HSA and FSA Accepted

While we cannot accept insurance, we do accept HSA and FSA payments.

Vitalife VIP Memberships

$75 per month